Searchable abstracts of presentations at key conferences in endocrinology

ea0031p156 | Neoplasia, cancer and late effects | SFEBES2013

Investigation of the antiproliferative effect of natural sesquiterpene lactones on human cancer cell lines

Molnar Judit , Lajter Ildiko , Hajdu Zsuzsanna , Szekeres Thomas , Saiko Philipp , Hohmann Judit , Zupko Istvan

Plants and plant extracts play a crucial role in the research of novel antineoplastic agents. Five sesquiterpene lactones, 4β,15-dihydro-3-dehydrozaluzanin C (ddZC), zaluzanin C, artecanin, 3β-chloro-4α,10α-dihydroxy-1α,2α-epoxy-5α,7αH-guaia-11(13)-en-12,6α-olide and iso-secotanapartholide methyl ether were isolated from two traditionally used Asteraceae species (Onopordum acanthium and Artemisia asiatica). MTT-assay was used to det...